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Figure 4 | Genetic Vaccines and Therapy

Figure 4

From: AAV-mediated gene therapy for metabolic diseases: dosage and reapplication studies in the molybdenum cofactor deficiency model

Figure 4

Reapplication at different developmental stages. EGFP expression two months after AAV-EGFP injection (filled triangles) following AAV expositions (open triangles) at different developmental stages. Animals received intrahepatic AAV-MOCS1 injections as indicated on top of the lines and an intrahepatic AAV-EGFP injection 2 months after the last AAV-MOCS1 injection. Liver sections of 2 animals are shown for each time point. Positive control animals (+) received only an AAV-EGFP injection. Negative controls (-) received no AAV. Further details are describe in figure 1.

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