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Figure 2 | Genetic Vaccines and Therapy

Figure 2

From: Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 ± IL-15

Figure 2

Specific cytolytic activity against HIV-1NL4-3 gp120 in mice immunized with SV(gp120) and assayed one month after final injection. BALB/cJ mice were immunized twice with SV(gp120) IP at monthly intervals. Splenocytes were harvested one month after final inoculation. Unselected effector cells were added to 51Cr-labelled target cells and specific lysis of gp120-expressing cells was calculated as described in Methods, ± S.E.M. Results shown here represent ≥ 3 independent determinations per data set.

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