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Figure 4 | Genetic Vaccines and Therapy

Figure 4

From: Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 ± IL-15

Figure 4

Specific cell-mediated responses against gp120-expressing target cells by splenic effectors from co-immunized mice Mice were given two monthly injections with either SV(mIL-15), SV(gp120) or both cytokine and antigen sequentially or simultaneously IP. One month after the final inoculation(s), unselected spleen cells were assayed for specific cytolytic activity against gp120-expressing clone 24 cells labeled with 51Cr, as described in Methods. Results shown here represent ≥ 3 independent determinations per data set.

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