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Figure 1 | Genetic Vaccines and Therapy

Figure 1

From: In vivogene targeting of IL-3 into immature hematopoietic cells through CD117 receptor mediated antibody gene delivery

Figure 1

Nested PCR detection of pIL3 plasmid in bone marrow 5, 7, and 10 days after injection of the conjugate. Mice were intravenously injected twice with 100μg of anti-CD117-pIL3 conjugate (at day 0 and at day 2). Control groups corresponded to bone marrow of mice treated with unconjugated pIL3 and anti-CD117 Abs or control conjugate (G250-pIL3). IL3 DNA and RNA were detected in the bone marrow of animals receiving the pIL3-anti CD117 conjugate up to day 10. The data are representative of three independent experiments.

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