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Table 1 Detection of circulating human IL-3 in mouse serum at day 5 post injection of pIL3 conjugate

From: In vivogene targeting of IL-3 into immature hematopoietic cells through CD117 receptor mediated antibody gene delivery

Treatment (IP injection)

Quantity of conjugate

pg/ml of human IL-3 in mice

Chloroquine

 

unconjugate

conjugate

  

mean

sd

mean

Sd

0

100μg

0

0

0

0

0

400μg

0

0

0

0

2 × 32.5 mg/kg

100μg

0

0

0

0

2 × 32.5 mg/kg

400μg

0

0

50*

17

  1. The presence of human IL-3 in serum was investigated by ELISA. The data are representative of three independent experiments and are the mean of triplicate determinations ± S.D. * indicates statistically significant differences by Student's t-test analysis; p < 0.007 as compared to 400μg of unconjugate.
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Genetic Vaccines and Therapy

ISSN: 1479-0556