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Figure 6 | Genetic Vaccines and Therapy

Figure 6

From: Recombinant adeno-associated virus type 2-mediated gene delivery into the Rpe65-/- knockout mouse eye results in limited rescue

Figure 6

Electron micrograph of injected and uninjected Rpe65-/- mouse retina Electron micrograph of the RPE of an rAAV.RPE65-injected Rpe65-/- mouse at 20 mo post injection (A) and an age-matched, uninjected Rpe65-/- control (21 mo of age; B). The injected animal shows an accumulation of retinyl ester lipid droplets in the RPE layer (small arrows) that is not as prevalent as that in the uninjected control. The layer of basal infoldings was also thinner in the injected mouse (large arrows). Scale bar = 5 μm.

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