Figure 1From: A dual function fusion protein of Herpes simplex virus type 1 thymidine kinase and firefly luciferase for noninvasive in vivoimaging of gene therapy in malignant gliomaCytotoxic and bioluminescent activity in U87MG glioma cells transiently transfected with different amounts of HSV-TK-Luc plasmid. (A) Cytotoxic activity as measured by MTT assay and (B) luciferase activity as determined luminometrically in cell lysates. Results are displayed as counts per second (cps)/ μg protein. (C) Linear regression analysis of cytotoxic activity plotted against luciferase activity for the different amounts of plasmid DNA. Results from 3 independent experiments were used.Back to article page