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Figure 1 | Genetic Vaccines and Therapy

Figure 1

From: Human cytomegalovirus plasmid-based amplicon vector system for gene therapy

Figure 1

Schematic representation of amplified region near oriLyt of the HCMV genome. A. Restriction enzyme map of minimal oriLyt and adjacent region of heterogeneity (block). B. Region of heterogeneity shown as a dimer. Arrow indicates junction of the repeat segment. The number 91,166 to the left of the restriction map corresponds to the nucleotide position of the AD169 genome (EMBL accession number X17403). C. Autoradiograph of Southern blot utilizing a minimal oriLyt probe, pON2623 (Kemble et al., 1996). Monomers and dimers are depicted with one and two arrows, respectively. Trimers and tetramers can be seen in the TownevarRIT viral stock.

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Genetic Vaccines and Therapy

ISSN: 1479-0556