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Table 2 List of the thirty transcripts showing the highest fluorescence signals in MEL02 amplified cRNA library

From: Production and characterization of amplified tumor-derived cRNA libraries to be used as vaccines against metastatic melanomas

 

Title

Symbol

Observations

1

Ribosomal protein L23a

RPL23a

 

2

Eukaryotic translation elongation factor 1 alpha 1

EEF1A1

 

3

Ribosomal protein S3A

RPS3A

 

4

RNase A family, 1 (pancreatic)

RNASE1

 

5

Peptidylprolyl isomerase A, cyclophilin A

PPIA

Overexpressed in several cancers [42]

6

Ribosomal protein S23

RPS23

 

7

Ribosomal protein L39

RPL39

 

8

Melan-A

MLANA

Melanoma differentiation antigen [2]

9

Ribosomal protein L31

RPL31

 

10

Cytochrome c oxidase subunit VIc

COX6C

Overexpressed in carcinomas [43]

11

Ribosomal protein L7

RPL7

Overexpressed in gliomas [44]

12

Ribosomal protein L37a

RPL37A

 

13

Ribosomal protein S29

RPS29

 

14

Secreted phosphoprotein 1, osteopontin

SPP1

Important for tumorgenesis [45]

15

Calmodulin 2

CALM2

Overexpressed in several cancers [42]

16

Ribosomal protein S11

RPS11

 

17

"Ribosomal protein S4, X-linked"

RPS4X

 

18

Nascent-polypeptide-associated complex alpha

NACA

Overexpressed in gliomas [44]

19

Ribosomal protein L23a

RPL23A

Involved in tumor proliferation [46]

20

ATP synthase, mitochondrial F0 complex, subunit g

ATP5L

 

21

Tubulin, alpha, ubiquitous

K-ALPHA-1

Overexpressed in breast cancers [47]

22

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex

NDUFA4

 

23

Ribosomal protein S27a

RPS27A

Overexpressed in breast cancers [48]

24

Beta-2-microglobulin

B2M

 

25

H2A histone family, member Z

H2AFZ

Overexpressed in several cancers [42]

26

SRY (sex determining region Y)-box 4

SOX4

Overexpressed in lung cancers [49]

27

ATP synthase, mitochondrial F1 complex, epsilon subunit

ATP5E

 

28

Tumor protein, translationally-controlled 1

TPT1

Involved in malignant transformation [50]

29

Cytochrome c oxidase subunit VIIa polypeptide 2

COX7A2

 

30

Ubiquitin B

UBB

Related to sustained proliferation [51]