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Figure 4 | Genetic Vaccines and Therapy

Figure 4

From: A combined nucleocapsid vaccine induces vigorous SARS-CD8+ T-cell immune responses

Figure 4

SARS-CoV-NC specific CD4+ T cell responses in mice immunized with the candidate vaccines. Fresh peripheral blood cells were cultured, stimulated with NC protein and stained for CD4, CD3 and IFN-γ. Flow cytometry was used to analyse the NC-specific CD4+T cell response. A negative control (without stimulation) and a positive control (phorbol myristate acetate + ionomycin) were included to control for the spontaneous production of IFN-γ(data not shown). Results are shown as mean ± S.D. The symbol † indicates a significant difference (P < 0.05) compared with the control group (DNA+XIAP).

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