Figure 1From: Comparison of different delivery systems of DNA vaccination for the induction of protection against tuberculosis in mice and guinea pigsIn vitro release profile of DNAhsp65 (▲) and recombinant hsp65 protein (■) encapsulated into PLGA derived microspheres. PLGA derived microspheres containing DNA or rHsp65 were ressuspended in PBS and maintained at 37°C under constant agitation. In pre-established time intervals, samples of the supernatant were collected and replaced with fresh buffer. The DNA or protein concentration in the supernatants were determined and represented as a percentage o cumulative release. Results are shown as mean μg ± SD from groups of five samples.Back to article page