Figure 7
From: Immunological analysis of a Lactococcus lactis-based DNA vaccine expressing HIV gp120
Non-specific immune stimulatory effect of vaccine plasmids. Splenocyte supernatants were collected before stimulation (day 0) and three days post stimulation with the plasmids (day 3). The secretion of IL-6 and IFN-γ was analysed by ELISA. Cross-sectioned bars: pLL120CpG, white bars: pLL120, grey bars: pEC120, black bars: pEC120CpG, and bars with vertical lines: culture medium. Symbols: +: DNase treatment of plasmid preparation. Error bars represent SD of two independent experiments.