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Figure 2 | Genetic Vaccines and Therapy

Figure 2

From: Respiratory syncytial virus infection in Fischer 344 rats is attenuated by short interfering RNA against the RSV-NS1 gene

Figure 2

siNS1 promotes IFN-γ production in the lung and reduces eosinophilia. Rats (n = 6) were treated with siNS1 or control vector, then 24 h later intranasally infected with RSV. Five days later bronchoalveolar lavage was done and levels of IFN-γ and IL-4 measured in the BAL supernatants (A-C). BAL cells were counted and the percentage of eosinophils (ephils) and lymphocytes (lyms) was determined by differential staining (D). Experiments were repeated twice and values are means ± SEM (*p < 0.05).

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Genetic Vaccines and Therapy

ISSN: 1479-0556