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Figure 6 | Genetic Vaccines and Therapy

Figure 6

From: Streamlined design of a self-inactivating feline immunodeficiency virus vector for transducing ex vivodendritic cells and T lymphocytes

Figure 6

Effect of pseudotyping LAW34 with different Env. A) Diagrammatic representation of the VSV-G and RD114/TR glycoproteins. The latter has the extracellular and transmembrane domains of the feline endogenous retrovirus RD114 and the cytoplasmic tail of an amphotropic murine leukemia virus [36]. Numbers are aa residues. B. Transduction efficiency for the indicated cell types of LAW34 pseudotyped with VSV-G (solid columns) or RD114/TR Env (empty columns). Bars and percent GFP-positive cells evaluated as in Fig. 4.

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Genetic Vaccines and Therapy

ISSN: 1479-0556