Figure 1
From: Tissue distribution of DNA-Hsp65/TDM-loaded PLGA microspheres and uptake by phagocytic cells
Tissue distribution of PLGA microspheres after intramuscular administration. Mice received a single intramuscular injection of fluorescent microspheres (DNA-Hsp65/TDM). At various time points (between 1 day and 120 days) the total cells from several tissues (draining lymph node, spleen, thymus, lung, liver, kidney, testicle and single-cell suspension of bone marrow) were obtained for FACS analysis (for each analysis, 100.000 events were acquired). Each group consisted of three or five animals. The results were shown as the median of positive values for each time. ×: in this time the results were negative.