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Table 2 Tissue distribution of PLGA microspheres after intramuscular administration

From: Tissue distribution of DNA-Hsp65/TDM-loaded PLGA microspheres and uptake by phagocytic cells

 

1d

7d

15d

30d

60d

120d

L Node

4

5

2

4

0

2

B Marrow

3

1

2

1

2

2

Spleen

5

3

2

2

0

1

Thymus

3

2

1

3

4

2

Lung

4

5

5

3

0

2

Kidney

4

3

3

0

5

0

Liver

5

2

3

0

5

2

Testicles

2

4

5

2

5

2

  1. The numbers in the columns indicate the number of the animals that presented positive detection of fluorescent microspheres in each organ evaluated at 1, 7, 15, 30, 60 (n = 5 mice) and 120 (n = 3 mice) days after intramuscular administration.