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Table 2 Tissue distribution of PLGA microspheres after intramuscular administration

From: Tissue distribution of DNA-Hsp65/TDM-loaded PLGA microspheres and uptake by phagocytic cells

  1d 7d 15d 30d 60d 120d
L Node 4 5 2 4 0 2
B Marrow 3 1 2 1 2 2
Spleen 5 3 2 2 0 1
Thymus 3 2 1 3 4 2
Lung 4 5 5 3 0 2
Kidney 4 3 3 0 5 0
Liver 5 2 3 0 5 2
Testicles 2 4 5 2 5 2
  1. The numbers in the columns indicate the number of the animals that presented positive detection of fluorescent microspheres in each organ evaluated at 1, 7, 15, 30, 60 (n = 5 mice) and 120 (n = 3 mice) days after intramuscular administration.
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Genetic Vaccines and Therapy

ISSN: 1479-0556