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Figure 2 | Genetic Vaccines and Therapy

Figure 2

From: Performance of AAV8 vectors expressing human factor IX from a hepatic-selective promoter following intravenous injection into rats

Figure 2

Determination of circulating human factor IX levels in blood plasma of AAV8hFIX infused rats. Blood plasma samples from scAAV8-LP1-hFIX infused rats at (black sqaure) 1 × 1010vg/rat, (black triangle) 5 × 1010vg/rat, (open triangle) 1 × 1011vg/rat, (open square) 5 × 1011vg/rat or (black circle) saline were assayed by ELISA to measure circulating hFIX activity. All values represent average hFIX levels with standard error of mean. Percentages refer to the percentage of normal circulating FIX levels.

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Genetic Vaccines and Therapy

ISSN: 1479-0556