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Figure 4 | Genetic Vaccines and Therapy

Figure 4

From: Retroviral vectors encoding ADA regulatory locus control region provide enhanced T-cell-specific transgene expression

Figure 4

Additional cis -regulatory elements further improve vector gene expression. A. SHGAL contains the human growth hormone polyadenylation signal (H) (pA in orange) 5' to the eGFP. 293A, Jurkat, Molt-4 and CEM cells were transduced by SAG, SiLAG or SHGAL vectors at MOI of 0.1. The MFI of eGFP expression (B) and the percentage of eGFP positive cells (C) were evaluated using FACS analysis.

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Genetic Vaccines and Therapy

ISSN: 1479-0556