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Figure 5 | Genetic Vaccines and Therapy

Figure 5

From: The effects of DNA formulation and administration route on cancer therapeutic efficacy with xenogenic EGFR DNA vaccine in a lung cancer animal model

Figure 5

Flow cytometry analysis EGFR-specific CD4+ and CD8+ T cells that functionally secrete IFN-γ in vaccinated mice. A) the number of IFN-γ-producing EGFR-specific CD4+ and CD8+ T cells in both spleens and inguinal lymph node was determined using flow cytometry in the presence of recombinant extracellular domain of human EGFR. B). Data are expressed as the mean numbers of CD4+ (black sqaure) and CD8+ (black sqaure)IFN-γ+ cells/3 × 105 spleen cells or inguinal lymph node cells; bars, SE. The symbol(**)indicates a statistically significant difference when compared with other treatment groups(P < 0.05). The data presented in this figure are from one representative experiment of two performed.

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Genetic Vaccines and Therapy

ISSN: 1479-0556