Skip to main content

Table 1 Infiltrated lymphocytes at tumor sites within cryosectioned samples

From: The effects of DNA formulation and administration route on cancer therapeutic efficacy with xenogenic EGFR DNA vaccine in a lung cancer animal model

Vaccine group

CD4+ T cells

CD8+ T cells

Control

6 ± 1

0

i.m

17 ± 2**

11 ± 5#

g.g -DNA coated gold particles

118 ± 24***

4 ± 3#

g.g-non coating DNA

7 ± 2

23 ± 4##

  1. Note: Cell count was performed at 400× magnification. Three samples and five randomly chosen fields/sample were evaluated. Results are expressed as mean ± standard deviation of immunohistochemical positive cells in the cryosection. GG: gene gun. The symbol (**) indicates a statistically significant difference when compared with the g.g non-coating DNA and control group (P < 0.05). The symbol (***) indicates a statistically significant difference when compared with the i.m and g.g non-coating DNA group (P < 0.05). The symbol (#) indicates a statistically significant difference when compared with the control group (P < 0.01). The symbol (##) indicates a statistically significant difference when compared with the i.m and g.g DNA coated gold particles group(P < 0.05).