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Figure 6 | Genetic Vaccines and Therapy

Figure 6

From: Protection against the allergic airway inflammation depends on the modulation of spleen dendritic cell function and induction of regulatory T cells in mice

Figure 6

Proliferation of peripheral CD 4 + (A) and CD 8 + T cells (B) and the expression of Foxp 3 + on spleen CD 4 + T cells (C) harvested from PBS-vaccinated mice sensitized and challenged with PBS, PBS-vaccinated mice sensitized and challenged with ovalbumon (OVA), pcDNA 3.1 -vaccinated mice sensitized and challenged with OVA, OVA- pcDNA 3.1 -vaccinated mice sensitized and challenged with OVA, and OVA-Fc-pcDNA 3.1 -vaccinated mice sensitized and challenged with OVA. * and ** stand for the p values less than 0.05 and 0.01, respectively, as compared with PBS-vaccinated mice sensitized and challenged with PBS. + and ++ stand for the p values less than 0.05 and 0.01, respectively, as compared with OVA-Fc-pcDNA3.1-vaccinated mice sensitized and challenged with OVA.

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