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Figure 1 | Genetic Vaccines and Therapy

Figure 1

From: A strategy of tumor treatment in mice with doxorubicin-cyclophosphamide combination based on dendritic cell activation by human double-stranded DNA preparation

Figure 1

Time course of Krebs-2 tumor growth in mice (mean ± SEM). Time course of Krebs-2 tumor growth in mice (mean ± SEM). Mice received 200 mg/kg CP and human DNA at a total dose 4.5-6 mg. After this treatment, one group of mice was pre-immunized with Krebs-2 tumor antigens by a s.c. injection of 20 × 106 repeatedly thawed-frozen tumor cells. The control group was injected with saline. Every group consisted of 10 mice. 106 Krebs-2 tumor cells were challenged i.m. after the treatment. Immunization enhanced the suppressive effect on tumor growth [31].

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Genetic Vaccines and Therapy

ISSN: 1479-0556