Figure 3

Effects of the chicken lysozyme (ChL) gene MAR on integrating (IN WT) and non-integrating (IN N) lentiviral vectors. Hela (a) and NIH-3T3 (b) and neural progenitor (c and d) cells were transduced with integrating (IN WT) or non-integrating (IN N) vectors containing a luciferase transgene expression cassette without (white columns) the ChL MAR or with a sense-oriented (black columns) or antisense-oriented (grey columns) ChL MAR. Statistical analysis was performed using a two-way ANOVA, and statistical significance of the Bonferroni post-test is represented on the relevant bars (* for p < 0.05, ** for p < 0.01 and *** for p < 0.001).