Figure 3
From: HCV entry receptors as potential targets for siRNA-based inhibition of HCV
Effect of silencing of HCV receptors by their specific siRNA on viral titer in Huh-7 cells. A) Viral titer in Huh-7 cells treated with scrambled siRNAs (Sc) or siRNAs of CD-81, LDL, SR and CLD and incubated for 6 hrs before adding HCV-3a sera (Ser 3a). HCV RNA levels were quantified by real-time PCR. Data are expressed as mean percent viral load of non-siRNA treated samples. Three independent experiments with triplicate determinations were performed. Error bars indicate, means plus or minus SD. *p < 0.01 vs. Ser3a.