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Figure 1 | Genetic Vaccines and Therapy

Figure 1

From: Plasmid-encoded NP73-102 modulates atrial natriuretic peptide receptor signaling and plays a critical role in inducing tolerogenic dendritic cells

Figure 1

NP73-102 is an inhibitor of NPRA signaling in hmDCs. (A) HmDCs were transfected with the indicated plasmids. The cells were collected 24 hr after transfection, lysed and immunoblotted with the indicated antibodies. (B) Cell viability of hmDCs by MTT assay 24 hr after plasmid transfection. (C) HmDCs were transfected with different doses of the indicated plasmids. The cells were collected 18 hr after transfection and intracellular cGMP was measured by ELISA. Analyses shown are representative of two or three independent experiments.

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