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Figure 2 | Genetic Vaccines and Therapy

Figure 2

From: Plasmid-encoded NP73-102 modulates atrial natriuretic peptide receptor signaling and plays a critical role in inducing tolerogenic dendritic cells

Figure 2

NP73-102 inhibition of NPRA signaling alters hmDC cytokine profile. (A-D) Transfected hmDCs were cultured in complete medium in 24-well plates for 24 hr. Cytokine levels in supernatants were measured in duplicate by cytokine bead array assay. The values are means ± SEM. *p < 0.05 and **p < 0.05 for NP73-102 vs pVAX and pANP respectively. (E) Immunoblotting for TGF-β expression in transfected DCs. (F) Protein bands were scanned and band density was quantitated using the Scion Image program. These results are from three separate experiments.

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Genetic Vaccines and Therapy

ISSN: 1479-0556