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Figure 4 | Genetic Vaccines and Therapy

Figure 4

From: Plasmid-encoded NP73-102 modulates atrial natriuretic peptide receptor signaling and plays a critical role in inducing tolerogenic dendritic cells

Figure 4

Natriuretic peptides modulate the expression of TLR2, STAT3 and SOCS3 in hmDCs. (A) HmDCs were transfected with the indicated plasmids, and cells were collected 24 hr after transfection for protein immunoblotting. (B-D) SOCS3, STAT3 and NF-κB reporter activities in DCs were measured after natriuretic peptide stimulation. The results shown are representative experiments from three independent assays.

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Genetic Vaccines and Therapy

ISSN: 1479-0556