Group | Apoptosis index(AI %) | P | ||
---|---|---|---|---|
 | HepG2 | HepG2-vector | HepG2-CDglyTK |  |
0.9% N S | 6.3 ± 1.0 | 5.7 ± 0.3 | 6.3 ± 1.3 | 0.43 |
GCV(5 μg/ml) | 7.1 ± 0.6 | 6.6 ± 0.7 | 7.2 ± 0.7 | 0.51 |
5-FC(100 μg/ml) | 6.8 ± 0.7 | 7.0 ± 1.0 | 7.0 ± 0.9 | 0.16 |
GCV(5 μg/ml)+5-FC(100 μg/ml) | 5.9 ± 0.5 | 6.1 ± 1.1 | 6.6 ± 1.1 | 0.18 |
P | 0.07 | 0.12 | 0.34 | Â |
 | L9981 | L9981-vector | L9981-CDglyTK |  |
0.9% N S | 5.1 ± 1.1 | 5.7 ± 1.3 | 5.4 ± 0.7 | 0.07 |
GCV(5 μg/ml) | 5.5 ± 0.3 | 6.0 ± 0.3 | 9.7 ± 1.7 | 0.04 |
5-FC(100 μg/ml) | 6.0 ± 0.8 | 6.7 ± 1.3 | 13.1 ± 2.7 | 0.031 |
GCV(5 μg/ml)+5-FC(100 μg/ml) | 6.1 ± 0.2 | 6.1 ± 1.1 | 19.9 ± 4.2 | 0.026 |
P | 0.19 | 0.17 | 0.012 | Â |
 | NL9980 | NL9980-vector | NL9980-CDglyTK | p |
0.9% N S | 6.0 ± 0.1 | 5.9 ± 0.3 | 5.8 ± 1.7 | 0.12 |
GCV(5 μg/ml) | 6.5 ± 0.2 | 6.3 ± 1.3 | 11.2 ± 2.4 | 0.03 |
5-FC(100 μg/ml) | 6.1 ± 0.8 | 5.7 ± 0.8 | 12.9 ± 3.6 | 0.024 |
GCV(5 μg/ml)+5-FC(100 μg/ml) | 5.9 ± 0.3 | 6.1 ± 1.5 | 23.1 ± 5.0 | 0.021 |
P | 0.11 | 0.11 | 0.0092 | Â |