Figure 7
LCMV pseudotyped FIV transduction persists in vivo. Luciferase expression was monitored up to 16 weeks following neonatal injection and signal intensities were quantified using Living Image 2.50 software. 100 μl of FIV-GP64 (an average of 1.0 × 107 TU), FIV-WE54 (~5.1 × 107 TU), or FIV-L260F (~1.2 × 107 TU) were injected via the facial vein 40-60 hours postnatally. Naïve mice received no injection. Images shown are representative of each condition. Animal groups n = 11 for FIV-GP64, 13 for FIV-WE54, and 17 for FIV-L260F. Standard errors are depicted with the average signal intensities.