Figure 3From: Treatment of adult MPSI mouse brains with IDUA-expressing mesenchymal stem cells decreases GAG deposition and improves exploratory behavior PCR analysis of transduced MSCs and treated mice. Genomic DNA isolated from MSCs from KO mice (A), brains from untreated KO mice (B), brains from wild-type mice (C), and brains from KO mice treated with MLV-IDUA-transduced MSCs (D) was used to analyze the IDUA and β-actin genes. The three molecular markers in the figures represent 300, 200 and 100 bp. N = PCR negative control; P = PCR positive control; I = IDUA; En = Endogenous β-actin; NT = non-transduced cells. The numbers on the figures indicate the number of each animal.Back to article page