Treatment of adult MPSI mouse brains with IDUA-expressing mesenchymal stem cells decreases GAG deposition and improves exploratory behavior

Table 4 GAG concentration in brains of mice treated with gene therapy

#	Groups	Total GAG	Mean ± SD	DS-HS (%)^a
11	WT 20w	1140.4	1566 ± 419	6.2
12	WT 20w	1281.2		9.9
13	WT 20w	1997.3		32.1
14	WT 20w	1849.6		29.0
1	WT 29w	NE	1907 ± 212	23.8
2	WT 29w	2057.0		NE
3	WT 29w	1757.3		9.8
15	KO 20w	2741.0	2443 ± 470	40.0
16	KO 20w	2889.3		48.8
24	KO 20w	1850.0		50.0
25	KO 20w	2290.0		48.2
4	KO 29w	4345.0	3234 ± 1287	49.8
5	KO 29w	3235.5		47.7
26	KO 29w	1429.0		43.5
27	KO 29w	3930.0		57.3
19	KO/IDUA 20w	1220.2	2065 ± 487	37.3
20	KO/IDUA 20w	2323.0		42.1
21	KO/IDUA 20w	2404.4		46.1
22	KO/IDUA 20w	2296.0		49.2
23	KO/IDUA 20w	2083.0		49.4
8	KO/IDUA 29w	1656.0	1509 ± 364	42.6
9	KO/IDUA 29w	1778.9		39.8
10	KO/IDUA 29w	1094.2		55.6