Figure 2From: In vivogene targeting of IL-3 into immature hematopoietic cells through CD117 receptor mediated antibody gene deliveryNested PCR detection of pIL3 plasmid in mononuclear peripheral blood cells 5, 7, and 10 days after injection of the conjugate. Mice were intravenously injected twice with 100μg of anti-CD117-pIL3 conjugate (at day 0 and at day 2). Control group corresponded to mononuclear peripheral blood cells or serum of mice treated with unconjugated pIL3 and anti-CD117 Abs. pIL3 DNA was only detected in peripheral blood of control animals until day 5 after the first injection. The data are representative of three independent experiments.Back to article page