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Figure 4 | Genetic Vaccines and Therapy

Figure 4

From: Recombinant adeno-associated virus type 2-mediated gene delivery into the Rpe65-/- knockout mouse eye results in limited rescue

Figure 4

Comparisons of photoreceptor numbers Photomicrographs of theouter retina of a 1 mo uninjected Rpe65-/- mouse (A), a 14 mo injected Rpe65-/- mouse (B) and a 14 mo C57BL/6J mouse (C). (D) Graphical presentation of the mean number of cells per 100 μm length of the outer nuclear layer (ONL) of C57BL/6J (▲), uninjected Rpe65-/- (◆) and rAAV.RPE65 injected Rpe65-/- (') at the various ages shown. All points are calculated from the cell numbers averaged over 3 animals unless indicated (*n = 1). Arrow indicates time of injection. Scale bar: A-C = 20 μm.

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Genetic Vaccines and Therapy

ISSN: 1479-0556