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Figure 7 | Genetic Vaccines and Therapy

Figure 7

From: ΔRR vaccination protects from KA-induced seizures and neuronal loss through ICP10PK-mediated modulation of the neuronal-microglial axis

Figure 7

ICP10PK induces IL-10 expression in ΔRR-infected microglia. EOC2 and EOC20 cells were mock-infected with PBS, or infected with ΔRR, ΔPK (moi = 5) or mock-infected with PBS and culture supernatants collected 1–72 hrs p.i. were assayed for IL-10 by ELISA, as described in Materials and Methods. Results are the mean of three independent experiments ± SD. (***p < 0.001 relative to ΔRR-infected).

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Genetic Vaccines and Therapy

ISSN: 1479-0556