Figure 6
From: Anti-tumor effects of a human VEGFR-2-based DNA vaccine in mouse models
CTL-mediated cytotoxicity in vitro. T lymphocytes from mice immunized with pORF-hFlk-1 LDC, pORF-mFlk-1 LDC, pORF-mcs LDC or GS were tested against murine MS1 cells at different effector/target ratios by 51Cr release assay. T cells isolated from mice immunized with pORF-hFlk-1 LDC showed increased cytotoxicity against Flk-1-positive target MS1 cells (P < 0.05). Points: means of triplicate samples from one representative experiment; bars: SE.