Vector reapplication in adolescence. Liver sections of adult mice after different treatment schemes. Exposure times (exp.) for EGFP are indicated (for further details see figure 1). A) First injection i.v. on day 40 with AAV-MOCS1, second injection intrahepatic with AAV-EGFP after 3 months. B) Only one intrahepatic AAV-EGFP injection 4 months after birth. C) No injection.