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Figure 3 | Genetic Vaccines and Therapy

Figure 3

From: Combined vascular endothelial growth factor-A and fibroblast growth factor 4 gene transfer improves wound healing in diabetic mice

Figure 3

Weak transgene expression in the skin of db/db mice 21 days after wounding and gene transfer. (A) Representative skin sections demonstrating β-galactosidase activity (arrows) in AAV-LacZ injected animal and the negative control (PBS treated skin). (B) Colorimetric assay showing slightly increased β-galactosidase activity in skin tissue homogenates from AAV-LacZ-injected animlas in comparison to the PBS-treated mice. (C) hVEGF and (D) hFGF4 protein in skin tissue homogenates measured by ELISA. Graphs represent means ± SEM (n = 5 animals/group); *p < 0.05 vs PBS and AAV-LacZ. Scale bar = 0.05 mm.

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Genetic Vaccines and Therapy

ISSN: 1479-0556