Table 1 Summary of statistically relevant effects of Igκ and ChL MARs on transduction efficiency on various cells in integrating (LV), double-copy (DC) and non-integrating (NILV) lentiviral vectors. (+) positive effect, (-) negative effect, (0) no effect.
| Â | Â | Vectors | ||||
|---|---|---|---|---|---|---|
|  |  | LV Igκ | DC Igκ | NILV Igκ | LV ChL | NILV ChL |
Cells | 293T | + | - | + | Â | Â |
| Â | Hela | 0 | - | - | Â | 0 |
| Â | 3T3 | + | 0 | - | Â | - |
| Â | Primary neural progenitors undifferentiated | Â | Â | 0 | 0 | 0 |
| Â | Primary neural progenitors differentiated | Â | Â | + | - | - |
| Â | Raji | 0 | Â | Â | Â | Â |
| Â | Jurkat | + | Â | Â | Â | Â |