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Figure 2 | Genetic Vaccines and Therapy

Figure 2

From: In vitro evaluation of a double-stranded self-complementary adeno-associated virus type2 vector in bone marrow stromal cells for bone healing

Figure 2

GFP Expression in Viral Transduced Cells 1 million rat and human bone marrow stromal cells (BMSCs) and 293T cells were transduced with AAV-GFP, LV-GFP and Ad-GFP and the GFP expression was assessed 48 hours after transduction. Non-transduced cells served as negative control. In comparison with the non-transduced controls, AAV-GFP transduced 293T cells show strong eGFP expression, but rat and human bone marrow stromal cells (BMSCs) did not exhibit expression levels as strong as 293T cells. LV-GFP and Ad-GFP transduced cells showed strong GFP expression in all transduced cell types except for Ad-GFP transduced 293T cells in which the viral replication causes cell death.

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Genetic Vaccines and Therapy

ISSN: 1479-0556