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Table 1 Vector Doses Administered In Vivo*

From: Altering α-dystroglycan receptor affinity of LCMV pseudotyped lentivirus yields unique cell and tissue tropism

Adult mice (luciferase vectors)++

 

FIV-GP64, 4 × 107 TU

 

FIV-WE54, 8 × 107 TU

 

FIV-L260F, 4 × 107 TU

 

Neonatal mice ++

 

Luciferase Vectors

β-Galactosidase Vectors

FIV-GP64, 1.0 × 107 TU

FIV-GP64, 2.0 × 107 TU

FIV-WE54, 5.1 × 107 TU

FIV-WE54, 5.0 × 106 TU

FIV-L260F, 1.2 × 107 TU

FIV-L260F, 4.0 × 106 TU

  1. *Presented as total number of transducing units (TU) delivered to each animal.
  2. ++Vectors administered to adult mice via tail vein. Vectors delivered to neonatal mice on day 2 of life via the facial vein (100 μl of centrifuge concentrated vector). The most concentrated preparations were used for each vector.
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Genetic Vaccines and Therapy

ISSN: 1479-0556